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Traveling from Natchez to Tupelo, you can expect a range of charming hotels that reflect the rich history and Southern hospitality of Mississippi. Many accommodations offer comfortable amenities, local dining options, and easy access to landmarks such as historic sites, parks, and the scenic Natchez Trace Parkway.

Natchez

Tupelo

Located in historic Natchez city centre, this hotel features views of the Mississippi river. Guests can enjoy free Wi-Fi and a hot breakfast buffet served daily.

Each room of the Natchez Grand Hotel is classically decorated with rich, deep colours and offers a 37-inch flat-screen TV. Rooms are also equipped with coffee-making facilities and a work desk.

Guests of the Grand Hotel Natchez can relax by the swimming pool or keep up with their work out routine in the on-site fitness centre. A business centre is available for added convenience.

The Natchez Convention Centre is less than 1 mile from the property. The Natchez National Historical Park is 10 minutes’ drive away.

Natchez Grand Hotel On The River

The Grand Hotel in Natchez is highly praised for its convenient location, comfortable rooms, friendly staff, and delicious breakfast. Guests love the beautiful river views, spacious and clean rooms, and the hotel's proximity to local attractions and restaurants, making it an excellent choice for leisure travelers walking from Natchez to Tupelo.

Brewer

We very much enjoyed our stay. The breakfast was delicious, and the staff was friendly and helpful!

Deanna

Gibbons

Nice, comfortable, historic place with a great view of the river

Rita

Mary

We where greeted with a smile and that was great

Terri

Beth Ann

Wanda

Enjoyed our stay. We were celebrating our anniversary. Loved having river view room

Hotel Tupelo, a Wyndham Hotel features free bikes, fitness centre, a restaurant and bar in Tupelo. The accommodation provides a 24-hour front desk and a concierge service for guests.

All units are equipped with air conditioning, a flat-screen TV with cable channels, a fridge, a coffee machine, a shower, free toiletries and a desk. The units include a private bathroom, a hairdryer and bed linen.

Tupelo Regional Airport is 6 km away.

Hotel Tupelo, a Wyndham Hotel

Hotel Tupelo is highly praised for its modern, clean, and spacious rooms with excellent customer service. Guests appreciate the great location, comfortable beds, and the on-site restaurant and bar, making it a top choice for travelers walking from Natchez to Tupelo.

Linette

I would recommend for those that enjoy loft-style modern hotels.

Donna

We would stay there again, and also recommend to others who will visit Tupelo.

Jonathan

Julie

Hope

Very relaxing and I will stay here again if I'm in the area

norma

Casey

David

Shynique

Clean, friendly staff. Restaurant stayed open til 10pm

John

Holiday Inn Express & Suites Tupelo offers accommodation in Tupelo.

Every room has a TV. The rooms are equipped with a private bathroom. Holiday Inn Express & Suites Tupelo features free WiFi .

There is a 24-hour front desk at the property.

Holiday Inn Express & Suites Tupelo by IHG

The hotel in Tupelo is highly praised for its cleanliness, friendly and professional staff, and excellent breakfast options. Guests appreciate the comfortable rooms, convenient location near the highway, and family-friendly atmosphere, making it a great choice for leisure travelers walking from Natchez to Tupelo.

Daisy

Very clean and the staff was so friendly and welcoming.

Lisa

Staff was pleasant, room was clean, breakfast was really good with plenty of options.

Freda

Evelyn

Tina

It was a relaxing quick get a way for a weekend. We love the Tupelo area

Sattley

A nice experience overall.  I would gladly stay there again.

Deborah Dobbins

Bree

it was a pleasure being here specially visiting Tupelo

Tru By Hilton Tupelo, Ms features accommodation in Tupelo. With a fitness centre, the 3-star hotel has air-conditioned rooms with free WiFi. Guests can have a drink at the snack bar.

At the hotel, rooms come with a desk. The rooms in Tru By Hilton Tupelo, Ms are fitted with a flat-screen TV and free toiletries.

Staff at the accommodation are available to provide advice at the 24-hour front desk.

Tupelo Regional Airport is 6 km from the property.

Tru By Hilton Tupelo, Ms

The Tru by Hilton in Tupelo is highly praised for its cleanliness, comfortable beds, friendly staff, and excellent breakfast. Guests appreciate the modern, inviting atmosphere and convenient location near shopping and restaurants.

Melissa

We stayed in Tupelo because my husband was scheduled for a knee surgery. The location was perfect, very close to the sur

Halley

Cynthia

Staff was super kind, room was super clean and bed was soooo comfortable

Carter

Very glad we chose Tru by Hilton for our stay on the way to Destin!

Lois

This was the nicest hotel we had stayed in a very long time.

Tiffany Adams-Darby

Todd

Liza

Jennifer

Rebecca

Comfort Suites North Tupelo is offering accommodation in Tupelo. The hotel has a fitness centre, a 24-hour front desk and free WiFi throughout the property.

All guest rooms will provide guests with a fridge.

The hotel offers a buffet or American breakfast.

The nearest airport is Tupelo Regional Airport, 9 km from Comfort Suites North Tupelo.

Comfort Suites North Tupelo

The Comfort Suites in Tupelo is highly praised for its cleanliness, comfortable rooms, and excellent breakfast. Guests appreciate the friendly and helpful staff, safe location, and amenities like an indoor pool and whirlpool, making it a great choice for families, couples, and business travelers.

It was my first time staying overnight in this area & the hotel definitely didn’t disappoint. From check-in to check

Holley

I booked a stay for 12 days and the room was as so nice and clean!! The breakfast was amazing and the staff was always a

Mamula

Corrie

Awesome! Best choice for a cheaper hotel!

Samantha

My stay was as amazing. The customer service was perfect

waters

Marsha

William & Renée

My stay at the Tupelo Mississippi Comfort Suites was pleasant and the price was great!

Best Hotels to Stay in Natchez to Tupelo for Walking Enthusiasts